October 2025 PVRI Community Call with Clara Hjalmarsson and Helen Christou

24 October 2025

In this PH Community Call, we discussed:

Risk Assessment Models and Event-Free Survival in Pulmonary Arterial Hypertension
PINK1/Parkin Deficiency Enhances Vascular Remodeling and Aggravates Hypoxia-induced Pulmonary Hypertension

Sandeep Sahay, Community Call Host

Joel James, Community Call Host

Tatiana Kudryashova, Community Call Host

Katarina Zeder, Community Call Host

Rodolfo Estrada, Community Call Host

Katrina Barry, Community Call Host

Clara Hjalmarsson, University Hospital Gothenburg, Sweden

Helen Christou, Brigham and Women's Hospital, Harvard Medical School

Other materials on this topic

19 December 2025

Pulmonary Hypertension Community Call — December

An on-demand recording of PVRI’s December PH Community Call, featuring informal discussion on emerging science and patient-focused research in pulmonary hypertension. The session covers new insights into hypoxic PH mechanisms and exercise interventions in PAH, with expert-led moderation and open exchange.

PVRI Community Calls

12 December 2025

Living Legend: Rubin Tuder, University of Colorado

In this Living Legends in PH session, Rubin Tuder reflects on a career that has shaped modern pulmonary hypertension research. He discusses key scientific advances, including the Sugen–hypoxia rat model, and shares personal insights on discovery, mentorship, and the evolution of the PH field, joined by Paul Hassoun and Jason Hong.

Members Only

2 December 2025

Identification of Diagnostic Biomarkers Causally Associated With Gut Microbiota and Pulmonary Arterial Hypertension

Pulmonary arterial hypertension (PAH) is a pulmonary disease associated with alterations in gut microbiota. We aimed to identify potential diagnostic genes causally associated with gut microbiota and PAH.

Pulmonary Circulation

1 December 2025

Beyond Resistance: Pulmonary Vascular Compromise as a Mechanistic Window Into Pediatric Pulmonary Hypertension

In the recent paper, Pulmonary Vascular Compromise is Associated with Survival in Pediatric Pulmonary Hypertension: a New Computational Model by Niccum et al. [1] presents an innovative computational model reframing pulmonary vascular disease through the concept of pulmonary vascular compromise (PVC), a quantifiable estimate of the proportion of pulmonary vascular surface area lost relative to an idealized normal pulmonary vascular capacity.