Pulmonary Hypertension Associated With COVID-19 Interstitial Lung Disease
Shreeya Mehta, Sophie Herbert, Konstantinos Dimopoulos, Bhavin Rawal, Benjamin Garfield, Melissa Heightman, Kate Myall, Bhashkar Mukherjee, Carl Harries, Heba Nashat, Colm McCabe, Anand Devaraj, Simon Bax, Gisli Jenkins, Athol U. Wells, Peter George, Elisabetta Renzoni, S. John Wort, Laura C. Price
https://doi.org/10.1002/pul2.70281
Abstract
Ten patients with post-COVID ILD-PH are described. This complication occurred only in patients after prolonged intensive care (ICU) admission for invasive mechanical ventilation. At the time of PH diagnosis by right heart catheterisation (RHC), all patients had high brain natriuretic peptide (BNP), impaired gas transfer at lung function testing, and elevated CT markers of PH including right to left ventricular dilatation (RV:LV ratio) and pulmonary artery to aortic ratios. Invasive haemodynamic assessment at RHC confirmed precapillary PH. These screening markers should prompt referral for echocardiography and to PH centres for consideration of RHC to confirm the diagnosis of ILD-PH.
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