Like a frontier, science is vast; it's endless. And like a pioneer entering a new land, when a scientist gazes across that expansive space, he sees opportunity and he sees freedom to pursue his thoughts and interests. Broadly speaking, there are two main types of scientists: the “basic” scientist, and the clinician. The basic scientist is most like the pioneer in that he has the most range to pursue his work, but unfortunately not always the most opportunity. The clinician is like the town doctor; he has access to all the clinical material, but not always the freedom or the knowledge to pursue the research necessary. But what happens when the basic scientist collaborates with the clinician? Results are found, science's unanswerable questions are solved, and clinical diagnosis and treatment of disease can be improved.