Advancing Clinical Trial Design in Pulmonary Hypertension

PVRI Member Authors: D. Dunbar Ivy, Steven Kawut, Mohammad Rahbar, Martin Wilkins

Abstract

In pulmonary hypertension, as in many other diseases, there is a need for a smarter approach to evaluating new treatments. The traditional randomized controlled trial has served medical science well, but constrains the development of treatments for rare diseases. A workshop was established to consider alternative clinical trial designs in pulmonary hypertension and here discusses their merits, limitations and challenges to implementation of novel approaches.

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Authors

Andy P. Grieve, Shien-Chung Chow, John Curram, Stephen Dawe, Lutz O. Harnisch, Noreen R. Henig, Hsien Ming J. Hung, D. Dunbar Ivy, Steven M. Kawut, Mohammad H. Rahbar, Shen Xiao, Martin R. Wilkins

Published in:

Pulmonary Circulation Vol 3: No 1 cover image

March 2013

Pulmonary Circulation Vol 3: No 1

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