Advancing Clinical Trial Design in Pulmonary Hypertension

PVRI Member Authors: D. Dunbar Ivy, Steven Kawut, Mohammad Rahbar, Martin Wilkins


In pulmonary hypertension, as in many other diseases, there is a need for a smarter approach to evaluating new treatments. The traditional randomized controlled trial has served medical science well, but constrains the development of treatments for rare diseases. A workshop was established to consider alternative clinical trial designs in pulmonary hypertension and here discusses their merits, limitations and challenges to implementation of novel approaches.

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Andy P. Grieve, Shien-Chung Chow, John Curram, Stephen Dawe, Lutz O. Harnisch, Noreen R. Henig, Hsien Ming J. Hung, D. Dunbar Ivy, Steven M. Kawut, Mohammad H. Rahbar, Shen Xiao, Martin R. Wilkins

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Pulmonary Circulation Vol 3: No 1 cover image

March 2013

Pulmonary Circulation Vol 3: No 1

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