Pulmonary hypertension in POEMS syndrome: resolution following radiotherapy

PVRI Member Authors: Andrew Peacock, Martin Johnson

Abstract

Pulmonary hypertension (PH) is defined by the presence of a mean pulmonary artery pressure (mPAP) ≥25 mmHg. It may be idiopathic or arise as a consequence of a number of diverse conditions. PH has been reported in association with POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal plasma cell disorder, and skin changes), with reversal following systemic treatment with corticosteroids. We report a case of pulmonary hypertension associated with POEMS syndrome treated with radical radiotherapy locally to bone lesions with resolution of systemic disease.

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Topics

Pulmonary Hypertension

Authors

Melanie J. Brewis, Alistair C. Church, Andrew J. Peacock, Stephen Thomson, Jane Tighe, and Martin K. Johnson

Published in:

Pulmonary Circulation Vol 4: No 4 cover image

December 2014

Pulmonary Circulation Vol 4: No 4

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