Complexity of macrophage migration inhibitory factor (MIF) and other angiogenic biomarkers profiling in pulmonary arterial hypertension

PVRI Member Authors: Wassim Fares

Abstract

Macrophage migration inhibitory factor (MIF) and 22 a priori selected biomarkers were measured from pulmonary arterial hypertension (PAH) patients. Significant positive correlations were found between MIF and several angiogenic factors suggesting a possible MIF regulation role in PAH angiogenesis and pathobiology, but simultaneously highlighting the biomarkers profiling complexity in PAH.

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Topics

Angiogenesis
Biomarkers
Pulmonary Arterial Hypertension

Authors

Jeffrey D. Marshall, Maor Sauler, Youlan Rao, Richard Bucala, Patty J. Lee

Published in:

Pulmonary Circulation Vol 7: No 3 cover image

September 2017

Pulmonary Circulation Vol 7: No 3

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