Understanding exercise hemodynamics

PVRI Member Authors: Horst Olschewski

The current definition of pulmonary hypertension as a resting mean pulmonary arterial pressure (mPAP) ≥25 mmHg is not based on scientific evidence but on expert opinion. It has been shown that below 25 mmHg, PAP may have an impact on survival and morbidity in patients with scleroderma and in lung disease such as chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis. Recently, the same has been shown in a large cohort of unselected patients.1The PAP increase during exercise may predict physical capacity2 and morbidity/mortality events.3

Published in:

Pulmonary Circulation Vol 7: No 3 cover image

September 2017

Pulmonary Circulation Vol 7: No 3

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