Right atrial mechanics provide useful insight in pediatric pulmonary hypertension

PVRI Member Authors: Brian Hanna

Abstract

Right atrial (RA) mechanics have been studied infrequently in children in the past due to technical constraints. With the advent of strain imaging, RA physiology can now be studied in greater detail. The principal aim of this study was to describe functional changes in right heart mechanics of children with idiopathic pulmonary arterial hypertension (PAH), by using new applications of RA strain. In this retrospective study, we evaluated RA mechanics of 20 patients (age range = 3–23 years) with PAH and 18 control patients. RA longitudinal strain (RALS) and longitudinal displacement (LD) were calculated by speckle-tracking echocardiography. RALS was plotted against LD, producing a characteristic strain-displacement (S-D) loop. Standard indices of right heart function and right heart catheterization data were obtained. Patients were clinically subdivided into “compensated” and “decompensated” PAH. A chart review was performed to identify patients who subsequently developed adverse outcomes, including death, awaiting or received lung and/or heart transplantation. . . . . 

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Topics

Pediatric
Pulmonary Arterial Hypertension
Pulmonary Hypertension
Right Heart Failure

Authors

Kyle D. Hope, Renzo José Carlos Calderón Anyosa, Yan Wang, Andrea E. Montero, Tomoyuki Sat, Anirban Banerjee

Published in:

Pulmonary Circulation Vol 8: No 1 cover image

March 2018

Pulmonary Circulation Vol 8: No 1

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