The blood gases in pulmonary arterial hypertension at rest show a normal or near-normal PaO2 but a low PaCO2 and a low HCO3-. In pulmonary hypertension due to lung disease PaO2 at rest is frequently low. Marked desaturation during exercise or at night is common in all forms of pulmonary hypertension.
Links to further reading:
- Hoeper MM, Pletz MW, Golpon H, Welte T. Prognostic value of blood gas analyses in patients with idiopathic pulmonary arterial hypertension. Eur Respir J 2007;29:944–950.
- The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS). 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. European Heart Journal (2016) 37, 67–119
- Peacock et al. Chapter 9. Clinical Features. In Pulmonary Circulation. Diseases and their Treatment Ed Peacock et al. 2016. 105-123