PVRI 2023/24 Digital: Breaking barriers in pulmonary hypertension

Next session:

13 December 2023

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PVRI 2023/24 Digital is a monthly webinar series of cutting edge science

We are delighted to introduce our new webinar series, PVRI 2023/24 Digital, launching November 2023. The series follows the success of our PVRI 2021/22 series and has been developed by Dr Patricia Thistlethwaite MD, PhD, University of California San Diego.


The monthly webinars will take place on the second Wednesday of each month at 15:00 BST/GMT and will feature keynote talks from senior experts in the field as well as young investigators. In addition to our in-person meetings and symposia, this series will enable us to connect with our worldwide community, but also allow us to continue to explore and discuss important new research. During the live sessions, there will be ample time set aside for Q&A to encourage active participation from our audience. 

Scientific programme

Controversies in Chronic Thromboembolic Pulmonary Hypertension: Pro-Con Debate

13 December 2023, 3PM GMT


  • Pro-con: All patients should have balloon pulmonary angioplasty before being referred for pulmonary endarterectomy Hiromi Matsubara (PRO) & Marcin Kurzyna (CON)
  • Pro-con: Pulmonary hypertension recurs after pulmonary endarterectomy in most patients Irene Lang (PRO) & Timothy Fernandes (CON)

Clinical Trials for Pulmonary Arterial Hypertension: What are we learning?

10 January 2024, 3PM GMT


  • ADVANCE Trial – Ralinepag – prostacyclin receptor agonist Fernando Torres 
  • Sotatercept phase 2 and phase 3 trials Mark Humbert 
  • TORREY Trial – Inhaled Seralutinib (PDGFR, CSFIR, c-Kit inhibitor) Robert Frantz 
  • INSIGNIA-PAH Trial – MK5475 inhaled soluble guanylate cyclase stimulator Maria Loureiro 
  • VIPAH-PRN Trial – Vardenafil inhaled phosphodiesterase type-5 inhibitor powder Veronica Franco 

Enhancing Drug Development for Paediatric Pulmonary Hypertension: An Integrative Perspective

14 February 2024, 3PM GMT


  • Clinical challenges in developing drug therapies for children with pulmonary hypertension Rolf Berger 
  • Challenges related to drug approval for children with pulmonary hypertension – regulatory perspective Christine Garnett 
  • Challenges facing pharmaceuticals in drug development for paediatric pulmonary hypertension Sylvia Nikkho 
  • Utility of Paediatric Registries for the characterization of pulmonary hypertensive phenotypes Maria Jesus del Cerro 

Ion Channels: Pathogenic Role and Therapeutic Intervention in Pulmonary Arterial Hypertension

13 March 2024, 3PM GMT


  • Mechanosensitive cation channels in the pulmonary vascular wall in pulmonary arterial hypertension Jason Yuan 
  • KCNK3 and ABCC8 Mutations in pulmonary vascular disease
  • Proton exchangers in pulmonary smooth muscle cells in pulmonary arterial hypertension Larissa Shimoda 
  • Pathophysiologic role of mutant potassium channels in pulmonary hypertension Angel Cogolludo 
  • Targeting KATP channels for treatment of pulmonary arterial hypertension

Single Cell Transcriptional Profiling in Lung Health and Pulmonary Arterial Hypertension

10 April 2023, 3PM BST


  • Update on the Human Lung RNAseq Atlas
  • Unsupervised transcriptomic profiling of whole blood shows biologic heterogeneity in iPAH Allan Lawrie 
  • Cellular landscape atlas of pulmonary endarterectomy tissue using single cell RNAseq
  • Single cell RNAseq identifies cellular abnormalities in rodent models of pulmonary hypertension Jason Hong 
  • Single-cell transcriptomic profiles of pulmonary artery endothelial cells in health and pulmonary arterial hypertension. 

More webinars to be announced soon!

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