01 January 2015 by Aaron Waxman, Marc Semigran

Changes in mPAP with inhaled NO predict and O2 survival in PAH

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Semigran {MJ},Hess D,Bloch {KD},Malhotra R,Lewis {GD},Waxman {AB}.Vasoreactivity to inhaled nitric oxide with oxygen predicts long-term survival in pulmonary arterial hypertension. [Internet]. 2011 ;1:250. Available from:http://www.pulmonarycirculation.org/text.asp?2011/1/2/250/83449

Changes in mPAP with inhaled NO predict and O2 survival in PAH. Kaplan-Meier survival curves for PAH patients stratified by vasoreactivity, defined by at least a 12% decrease in mPAP with vasodilator challenge. The Log-rank test demonstrates reduced mortality in vasoreactive patients (P=0.049).

 

Additional keywords: NO,nitric oxide,follow-up,mean pulmonary artery pressure

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