01 January 2015 by Max Gassmann

During anaerobic glycolysis, glucose is transformed to pyruvate

stergaard L,Gassmann M.Hypoxia Inducible Factor and Hypoxia-mediated Pulmonary Hypertension. [Internet]. 2011 ;3:5. Available from:http://pvrireview.org/article.asp?issn=0974-6013;year=2011;volume=3;issue=1;spage=5;epage=11;aulast=%D8stergaard

During anaerobic glycolysis, glucose is transformed to pyruvate. As the name indicates, this takes place when O2 is limited, during, for instance, hypoxic exposures or intense exercise. Two ATP molecules per glucose molecule or about 5% of glucose's energy potential (38 ATP molecules) are produced in this process, making it highly energy inefficient, except that the speed at which ATP is produced is about 100 times that of oxidative phosphorylation. Prolonged anaerobic glycolysis generally leads to lactic acidosis, which is a decrease in the pH. level of the blood.


Additional keywords: gluscose,glycolysis,lactate,oxidative phosphorylation,mitochondrion

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Max Gassmann

Director of the Institute of Veterinary Physiology


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