Original figure adapted from data in Andersen et al.(a): In chronic hypoxic rats, lung concentrations of apelin were not altered in the same direction as plasma apelin by hypoxia and sildenafil treatment. (b): Right ventricular apelin concentrations correlated weakly with plasma apelin levels; (c): Plasma apelin levels were not correlated to right ventricular systolic pressure. RVSP: Right ventricular systolic pressure. = Normoxic rats; = Hypoxic rats, = Hypoxic rats treated with sildenafil 25 mg/kg/day. ;(1) Andersen CU,Markvardsen LH,Hilberg O,Simonsen U.Pulmonary apelin levels and effects in rats with hypoxic pulmonary hypertension.Respir Med. 2009 ;103(11):1663-71.
Additional keywords: apelin,factor,right ventricle,lung