01 January 2015 by Merryn Tawhai

Schematic of contributions to distribution of blood

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Tawhai {MH},Burrowes {KS},Clark {AR}.Computational models of the pulmonary circulation: Insights and the move towards clinically directed studies. [Internet]. 2011 ;1:224. Available from:http://www.pulmonarycirculation.org/text.asp?2011/1/2/224/83452

Schematic of contributions to distribution of blood. (A) Vascular asymmetry contributes to heterogeneity, and decrease in perfusion in the extremities; (B) hydrostatic pressure gradient acts directly on blood to drive it preferentially downwards, and introduces a constraint at the capillary level; (C) deformation of tissue establishes a gravitational gradient of vessels per unit tissue, enhancing the flow gradient; also contributes to reduction in flow in most dependent region; (D) combined result is a gravitational gradient and isogravitational heterogeneity, each affected by multiple mechanisms.

 

Additional keywords: factors,distribution,hydrostatics,structure,tissue deformation

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