open/close global search bar

01 January 2015 by Dr. Josh Fessel, James (Jim) Loyd, Dr. Eric Austin

Atlas image

Simplified canonical TGF-/BMP signaling and non-canonical signaling unique to BMPR2

AI00066.jpg
Fessel {JP},Austin {ED},Loyd {JE}.The genetics of pulmonary arterial hypertension in the post-{BMPR2} era. [Internet]. 2011 ;1:305. Available from:http://www.pulmonarycirculation.org/text.asp?2011/1/3/305/87293

Simplified canonical TGF-/BMP signaling and non-canonical signaling unique toBMPR2. The dashed line delineates canonical TGF- signaling (on the left) from some of the pathways interacting withBMPR2via its long cytoplasmic tail.

 

Additional keywords: TGF beta,BMP,Smad,Alk

Authors

profile picture of Dr. Josh Fessel

Dr. Josh Fessel
profile picture of James (Jim) Loyd

James (Jim) Loyd
profile picture of Dr. Eric Austin

Dr. Eric Austin

Related Content

EMA Perspective: Post-IMPRES, what is the future of TKI in PH Therapy? thumbnail image

Conference talk

27 January 2014

{{GlobalController.truncateTitle("EMA Perspective: Post-IMPRES, what is the future of TKI in PH Therapy?", 65)}}
Histopathology images of pulmonary vascular disease: Intimal proliferative lesion in a pre-acinar artery thumbnail image

Atlas image

01 January 2015

{{GlobalController.truncateTitle("Histopathology images of pulmonary vascular disease: Intimal proliferative lesion in a pre-acinar artery", 65)}}
Histopathology images of pulmonary vascular disease: Intimal proliferative lesions thumbnail image

Atlas image

01 January 2015

{{GlobalController.truncateTitle("Histopathology images of pulmonary vascular disease: Intimal proliferative lesions", 65)}}
Diagram of pre- and post-test probabilities for developing HPAH in an unaffected family member, and the mathematical impact of testing for BMPR2 mutation thumbnail image

Atlas image

01 January 2015

{{GlobalController.truncateTitle("Diagram of pre- and post-test probabilities for developing HPAH in an unaffected family member, and the mathematical impact of testing for BMPR2 mutation", 65)}}
This family carries a mutation in the ligand-binding domain of BMPR2 thumbnail image

Atlas image

01 January 2015

{{GlobalController.truncateTitle("This family carries a mutation in the ligand-binding domain of BMPR2", 65)}}

Add to reading list

Please enter a list name.

Our research platform is the world.

Through worldwide collaboration, we can begin to answer the question of a global disease.

Join the PVRI
standard-example-image.jpg