01 January 2015 by Dr. Josh Fessel, James (Jim) Loyd, Dr. Eric Austin

Simplified canonical TGF-/BMP signaling and non-canonical signaling unique to BMPR2

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Fessel {JP},Austin {ED},Loyd {JE}.The genetics of pulmonary arterial hypertension in the post-{BMPR2} era. [Internet]. 2011 ;1:305. Available from:http://www.pulmonarycirculation.org/text.asp?2011/1/3/305/87293

Simplified canonical TGF-/BMP signaling and non-canonical signaling unique toBMPR2. The dashed line delineates canonical TGF- signaling (on the left) from some of the pathways interacting withBMPR2via its long cytoplasmic tail.

 

Additional keywords: TGF beta,BMP,Smad,Alk

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