24 February 2022

Bone marrow modulation of pulmonary vascular disease

Watch the replay

Agenda

  • James West // Reversal of PH by whole bone marrow transplantation in BMPR2 deficient mice
  • Norbert Weissmann // Bone marrow dependency of cigarette smoke-induced PH versus emphysema
  • Jason Weatherald // Homologous bone marrow transplantation prevents the development of PAH in patients with severe scleroderma
  • Gaurav Choudhary // Role of bone marrow in the right ventricle remodelling

Poll results

1. Talk 1: Inflammation and bone marrow-derived cells play an important role in pulmonary vascular remodelling

Agree - 100%

Disagree - 0%

 

2. Talk 2: The inducible nitric oxide synthase in bone marrow-derived cells is a major driver of cigarette smoke-induced pulmonary hypertension in mice

Agree - 82%

Disagree - 18%

 

3. Talk 3: Autologous stem cell transplantation warrants further research as a therapeutic or preventative option for at-risk systemic sclerosis-associated PAH

Agree - 100%

Disagree - 0%

 

4. Talk 4: Bone Marrow derived cells play an important role in RV remodelling in pulmonary hypertension

Agree - 82%

Disagree - 18%


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