04 May 2022
The association between cancer and PH: A tale of two diseases
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Agenda
- Timothy Morris // Cancer induced PH: Embolism as a major inducer
- Rajkumar Savai // Cancer induced PH: Microenvironmental cancer niche as a major inducer
- Frédéric Perros // Cancer therapies induced PH
- Olivier Boucherat // Cancer related signalling mechanisms underlying PH development
- Yann Grobs // FOXO3: A new potential therapeutic target in pulmonary arterial hypertension
- Michael Cekay // Non-invasive surrogate markers of PH are associated with poor survival in lung cancer patients
Poll results
1. N/A
2. Talk 2: PH impacts the lung cancer prognosis and survival
Agree - 100%
Disagree - 0%
3. Talk 3: Current animal models of pulmonary hypertension, acute and hyperproliferative in nature, do not predict the effect of anti-cancer therapies in the setting
Yes - 100%
No - 0%
4. Talk 4: Should we focus on signaling pathways identified in cancer to find new actionable targets in PAH?
Yes - 100%
No - 0%
5. Talk 5: TFP is an antagonist of calmodulin and has a cardioprotective effect on left ventricle. In PAH, do you think TFP treatment could improve hemodynamic parameters by playing a role on lung and right ventricle maladaptive remodeling?
Yes - 75%
No - 25%
Talk 6: Lung cancer patients with pulmonary hypertension may profit from guidelines based pulmonary hypertension therapy.
Agree - 75%
Disagree - 25%