A ventilation/perfusion lung scan should be performed in patients with pulmonary hypertension because it has the highest sensitivity for chronic thromboembolic pulmonary hypertension (CTEPH). A normal or low probability scan can exclude CTEPH with a sensitivity and specificity both greater than 90%.
Links to further reading:
- Tunariu N, Gibbs SJR, Win Z, Gin-Sing W, Graham A, Gishen P, AL-Nahhas A.Ventilation-perfusion scintigraphy Is more sensitive than multidetector CTPA in detecting chronic thromboembolic pulmonary disease as a treatable cause of pulmonary hypertension. J Nucl Med 2007;48:680–684.
- The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS). 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. European Heart Journal (2016) 37, 67–119
- Sproule, M. Chapter 8. Imaging. In Pulmonary Circulation. Diseases and their Treatment Ed Peacock et al. 2016. 138-152