Sex Differences in Right Heart Remodeling: Oestrogenic Angiogenesis and RV Adaptation to Pressure Overload

Ketul Chaudhary

Ketul Chaudhary is an assistant professor in the Department of Physiology & Biophysics, Dalhousie University. He's is a basic science researcher with research interest in understanding the sex differences in cardiopulmonary physiology and pathophysiology of cardiopulmonary diseases. His research has provided novel insight into pathophysiology of pulmonary arterial hypertension (PAH) and uncovered the role of hemodynamic stress, endothelial cell apoptosis and female sex hormones in pathophysiology of PAH. His team has recently identified novel mechanisms of sex differences in right ventricle endothelial cell function and its relevance to sex differences in right (-sided) heart failure. Dr. Chaudhary seeks to promote meaningful collaboration among basic science researchers (including trainees), patients, and clinician-researchers to address critical knowledge gaps in women’s cardiovascular health and develop novel therapies for cardiopulmonary diseases. Currently, research in his laboratory is supported by the Project grant from Canadian institute of health research, John R. Evans Leaders Fund from Canada Foundation for Innovation and the national new investigator award from the Heart and Stroke Foundation of Canada.