Learning and research

An on-demand recording of PVRI’s December PH Community Call, featuring informal discussion on emerging science and patient-focused research in pulmonary hypertension. The session covers new insights into hypoxic PH mechanisms and exercise interventions in PAH, with expert-led moderation and open exchange.

Cole Uhland and Franz P Rischard discuss Treatment Response and Survival in Methamphetamine-Associated Pulmonary Arterial Hypertension in November’s informal, open-access Community Call.

In this PH Community Call we discussed: 

• Risk Assessment Models and Event-Free Survival in Pulmonary Arterial Hypertension
• PINK1/Parkin Deficiency Enhances Vascular Remodeling and Aggravates Hypoxia-induced Pulmonary Hypertension

In this PH Community Call we discussed: 

• Adventitial fibroblasts direct smooth muscle cell-state transition in pulmonary vascular disease
• Hemodynamics and Phosphodiesterase-5 Inhibitor Treatment Associated with Survival in ILD-PH: A PVRI GoDeep Meta-Registry Analysis 

In this Community Call, we discussed:

• Epicardial adipose tissue as an independent risk factor for mortality in pulmonary arterial hypertension
• Morbidity and mortality associated with pulmonary arterial hypertension in a schistosomiasis‐endemic region of Brazil

In this Community Call, we discussed:

• Positioning Imatinib for pulmonary arterial hypertension: A dose finding phase 2 study
• Mitochondria as a primary determinant of angiogenic modality in pulmonary arterial hypertension

In this Community Call, we discussed:

• Defining echocardiographic degrees of right heart size and function in pulmonary vascular disease from the PVDOMICS study
• Skeletal muscle SIRT3 deficiency contributes to pulmonary vascular remodeling in pulmonary hypertension due to heart failure with preserved ejection fraction

In this Community Call, we discussed:

• An electrocardiogram-based AI algorithm for early detection of pulmonary hypertension
• Branched-chain α-ketoacids aerobically activate HIF1α signalling in vascular cells

In this Community Call, we discussed:

• Deep phenotyping of unaffected carriers of pathogenic BMPR2 variants screened for pulmonary arterial hypertension
• Pulmonary hypertension induced by right pulmonary artery occlusion: hemodynamic consequences of Bmpr2 mutation