Learning and research

In this PH Community Call, we discussed: 

• Subcutaneous Treprostinil in PH Associated With Left Heart Disease or Chronic Lung Disease
• Ferroportin Inhibition Attenuates Pulmonary Hypertension in Hypoxic Sickle Cell Disease Mice 
• Artificial Intelligence-Based Echocardiography in Pulmonary Arterial Hypertension 

In this PH Community Call, we discussed: 

• Monocytes and interstitial macrophages contribute to hypoxic pulmonary hypertension 
• Effects of kettlebell exercise training on functional capacity and metabolic costs of activities of daily living in patients with pulmonary arterial hypertension: A randomized controlled trial - ScienceDirect 

In this PH Community Call, we discussed: 

• Treatment Response and Survival in Methamphetamine‐Associated Pulmonary Arterial Hypertension

In this PH Community Call we discussed: 

• Risk Assessment Models and Event-Free Survival in Pulmonary Arterial Hypertension
• PINK1/Parkin Deficiency Enhances Vascular Remodeling and Aggravates Hypoxia-induced Pulmonary Hypertension

In this PH Community Call we discussed: 

• Adventitial fibroblasts direct smooth muscle cell-state transition in pulmonary vascular disease
• Hemodynamics and Phosphodiesterase-5 Inhibitor Treatment Associated with Survival in ILD-PH: A PVRI GoDeep Meta-Registry Analysis 

In this Community Call, we discussed:

• Epicardial adipose tissue as an independent risk factor for mortality in pulmonary arterial hypertension
• Morbidity and mortality associated with pulmonary arterial hypertension in a schistosomiasis‐endemic region of Brazil

In this Community Call, we discussed:

• Positioning Imatinib for pulmonary arterial hypertension: A dose finding phase 2 study
• Mitochondria as a primary determinant of angiogenic modality in pulmonary arterial hypertension

In this Community Call, we discussed:

• Defining echocardiographic degrees of right heart size and function in pulmonary vascular disease from the PVDOMICS study
• Skeletal muscle SIRT3 deficiency contributes to pulmonary vascular remodeling in pulmonary hypertension due to heart failure with preserved ejection fraction

In this Community Call, we discussed:

• An electrocardiogram-based AI algorithm for early detection of pulmonary hypertension
• Branched-chain α-ketoacids aerobically activate HIF1α signalling in vascular cells