Association of mildly elevated pulmonary vascular resistance with major cardiovascular events in pulmonary hypertension and chronic kidney disease: A retrospective cohort analysis

17 June 2024

Jose M. Martinez ManzanoAlexander PrendergastTara JohnRaul LeguizamonIan McLarenRasha KhanAndrew GellerPhuuwadith WattanachayakulJohn MalinSimone A. JarrettKevin Bryan LoSadia BenzaquenChristian Witzke

https://doi.org/10.1002/pul2.12401

Abstract

Pulmonary hypertension (PH) is associated with adverse outcomes in chronic kidney disease (CKD) patients. Our study suggests mildly elevated pulmonary vascular resistance ( > 2 to ≤ 3) is independently associated with major adverse cardiovascular events at 1-year follow-up. Early diagnosis of precapillary PH in CKD patients can potentially improve clinical outcomes.

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