Comorbidities and Events of Clinical Interest in Patients with Pulmonary Arterial Hypertension (PAH): Analysis of Real-World Data

7 April 2026

Julia R. DiBello, Dena Rosen Ramey, Alexandra G. Cornell, Harald Sinclair Mackenzie, Tammy Jiang, Michelle Skornicki, Dionna Andrean, Jackie Lucia, Ioana R. Preston

https://doi.org/10.1002/pul2.70288 

 

Abstract

Pulmonary arterial hypertension (PAH) patients frequently present with cardiometabolic comorbidities and experience substantial hematologic and cardiovascular events. In a retrospective U.S. linked claims-EHR cohort (n = 16,749), hypertension, heart failure, diabetes, and CKD were common. Incidence rates (per 100 person-years) for thrombocytopenia and major bleeding were 8.2 and 7.3, respectively.

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