Initial Experience of Multipurpose Mechanical Aspiration System for Acute High-Risk Pulmonary Embolism: A Prospective Multi-Center Case Series
GuangMing Tan, Timothy Ho Him Kam, Edbert Cheuk Yin Lai, Esmond Yan Hang Fong, Jake Yin Kei Yeung, Bryan Ping-Yen Yan
https://doi.org/10.1002/pul2.70206
Abstract
High-risk acute pulmonary embolism (PE) is associated with significant in-hospital mortality. Large-Bore Mechanical Thrombectomy (LBMT) is a treatment option for acute PE, but data on its efficacy in high-risk PE was limited. This prospective case series reported the outcomes of 14 patients with high-risk PE treated using a novel multipurpose mechanical aspiration system (MMAS). Most patients were in hemodynamic decompensation, requiring inotropic or mechanical circulatory support. The mean procedural time was 73.5 ± 39.2 min. Complete procedural success was achieved in 78.6% of the cases, while two patients required bailout therapies. The mean pulmonary arterial pressure decreased by 27.2%, and the right-ventricle/left-ventricle ratio normalized in 85.7% of patients. The primary endpoint—in-hospital mortality—was 0%, while the major bleeding rate was 27.2%. These findings suggest that MMAS is a safe and effective intervention for acute high-risk PE.
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