Learning & research

In this PH Community Call, we discussed: 

• CES1 Deficiency is Associated With Metabolic Reprograming and Endothelial Dysfunction in Pulmonary Arterial Hypertension by Stuti Sunil Kumar Agarwal
• Impaired Lung BCAA Metabolism Promotes Ferroptosis and Resultant Pulmonary Arterial Hypertension-Associated Hepatopathy by Madelyn Blake

In this PH Community Call, we discussed: 

• Sotatercept in Pulmonary Arterial Hypertension: Central, Hematologic, and Peripheral Mechanisms of Benefit
  Sotatercept improves small airway disease and hyperinflation in patients with pulmonary hypertension

In this PH Community Call, we discussed: 

• C–C Motif chemokine receptor-2 blockade ameliorates PH in rats and synergizes with a pulmonary vasodilator
• Deep-learning networks accurately detect pulmonary hypertension in patients with idiopathic pulmonary fibrosis
• Assessing the feasibility of using smartphone data to identify risk of idiopathic pulmonary arterial hypertension

In this PH Community Call, we discussed: 

• Breast Cancer Reveals Latent BMPR2-Related Susceptibility to Pulmonary Hypertension
• Predicting pulmonary hypertension in infants with bronchopulmonary dysplasia
• Acute Hemodynamic Effects of Sotatercept

In this PH Community Call, we discussed: 

• Subcutaneous Treprostinil in PH Associated With Left Heart Disease or Chronic Lung Disease
• Ferroportin Inhibition Attenuates Pulmonary Hypertension in Hypoxic Sickle Cell Disease Mice 
• Artificial Intelligence-Based Echocardiography in Pulmonary Arterial Hypertension 

In this PH Community Call, we discussed: 

• Monocytes and interstitial macrophages contribute to hypoxic pulmonary hypertension 
• Effects of kettlebell exercise training on functional capacity and metabolic costs of activities of daily living in patients with pulmonary arterial hypertension: A randomized controlled trial - ScienceDirect 

In this PH Community Call, we discussed: 

• Treatment Response and Survival in Methamphetamine‐Associated Pulmonary Arterial Hypertension

In this PH Community Call we discussed: 

• Risk Assessment Models and Event-Free Survival in Pulmonary Arterial Hypertension
• PINK1/Parkin Deficiency Enhances Vascular Remodeling and Aggravates Hypoxia-induced Pulmonary Hypertension

In this PH Community Call we discussed: 

• Adventitial fibroblasts direct smooth muscle cell-state transition in pulmonary vascular disease
• Hemodynamics and Phosphodiesterase-5 Inhibitor Treatment Associated with Survival in ILD-PH: A PVRI GoDeep Meta-Registry Analysis 

In this Community Call, we discussed:

• Epicardial adipose tissue as an independent risk factor for mortality in pulmonary arterial hypertension
• Morbidity and mortality associated with pulmonary arterial hypertension in a schistosomiasis‐endemic region of Brazil