Iron and High Altitude
4 November 2025
4 November 2025, 13:00 GMT
Part of the 'Hypoxia in pulmonary vascular research – altitude and beyond' webinar series by the High Altitude Task Force, who raise awareness and understanding of PH linked to high altitude and organise scientific conferences in regions affected by high altitudes. Our webinars are free and open to all.
- Iron and High Altitude Martina Muckenthaler, University Hospital Heidelberg
Our speaker
Martina Muckenthaler is Professor of Molecular Medicine at the Medical University of Heidelberg, where she leads research within the Center of Translational BioIron Research. Her work focuses on human iron metabolism and the molecular mechanisms underlying iron overload and deficiency disorders.
Her team investigates the physiological regulation of iron homeostasis and its disturbances in human disease, using both cellular systems and murine disease models. A particular area of interest is how iron metabolism adapts to hypoxic conditions, such as at high altitude.
Recent key publications include:
- Gassmann M, Muckenthaler MU. Adaptation of iron requirement to hypoxic conditions at high altitude. J Appl Physiol. 2015;119(12):1432–40.
- Muckenthaler MU, Mairbäurl H, Gassmann M. Iron metabolism in high-altitude residents. J Appl Physiol (1985). 2020;129(4):920–925.
- Galy B, Conrad M, Muckenthaler M. Mechanisms controlling cellular and systemic iron homeostasis. Nat Rev Mol Cell Biol. 2024;25(2):133–155.
Speakers & moderators
Martina Muckenthaler, University Hospital Heidelberg, Germany
Aastha Mishra, CSIR-Institute of Genomics & Integrative Biology, India
Silvia Ulrich, University Hospital Zurich, Switzerland
More from PVRI High Altitude Webinar Series
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The 'Hypoxia in pulmonary vascular research – altitude and beyond' webinar series is organised by the High Altitude Task Force, who raise awareness and understanding of PH linked to high altitude and organise scientific conferences in regions affected by high altitudes.