Learning and research

A comprehensive library of abstracts, scientific talks, scientific papers, and research on pulmonary vascular disease

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20 March 2025

159 meeting abstracts from PVRI 2025 Rio.

Pulmonary Circulation
20 March 2025

Pulmonary arterial hypertension (PAH) is characterized by progressive narrowing and obliteration of distal, pre-capillary pulmonary vessels. Yet, noninvasive biomarkers that reflect this disease-defining process are lacking. A systematic review of PAH studies that measured circulating progenitor cells (CPCs) or circulating endothelial cells (CECs) in PAH by flow cytometry was performed to understand how future studies, leveraging state-of-the-art single-cell analyses, can advance the field.

Pulmonary Circulation
11 March 2025

Pulmonary embolism (PE) is a leading cause of mortality in lung transplant recipients, with early cases associated with particularly poor outcomes. Identified risk factors include elevated BMI, renal dysfunction, ABO mismatch, donor malignancy, and specific immunosuppressive agents. Tailored risk assessments and targeted interventions are essential to mitigating PE-related mortality.

Pulmonary Circulation
3 March 2025

Benchmarks of clinical management are essential for improving the quality of care. However, the lack of established quality metrics for pulmonary arterial hypertension (PAH) contributes to practice heterogeneity. We assessed our center's diagnostic practices, therapeutic practices, and risk-adjusted survival patterns over time for the purpose of establishing quality benchmarks. 

Pulmonary Circulation
27 February 2025

In this Community Call, we discussed:

  • Defining echocardiographic degrees of right heart size and function in pulmonary vascular disease from the PVDOMICS study
  • Skeletal muscle SIRT3 deficiency contributes to pulmonary vascular remodeling in pulmonary hypertension due to heart failure with preserved ejection fraction
PVRI Community Calls