The impact of gas transfer on responses to exercise training in patients with pulmonary hypertension

25 September 2024

Ciara McCormackBrona KehoeBrian McCullaghSean GaineNiall M. MoynaSyed Rehan Quadery

https://doi.org/10.1002/pul2.12438

Abstract

Exercise training is recommended for pulmonary hypertension (PH). Post hoc analysis of the PH and Home-Based (PHAHB) trial stratified patients into two groups based on median diffusing capacity of the lungs for carbon monoxide (DLCO). Patients with higher DLCO had a greater improvement in physical activity performance in response to exercise training, compared to those with lower DLCO. DLCO may be an important consideration in prescribing exercise in PH.

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