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10 October 2025

This PVRI Digital Webinar is part of the 'Living Legends in PH: History & Personal Perspectives' session. Features:

  • Living Legend: Lewis Rubin, University of California San Diego
  • Senior facilitator: Jason Yuan, University of Florida 
  • Junior facilitator: Jose Gomez-Arroyo, University of Cincinnati
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12 September 2025

This PVRI Digital Webinar is part of the 'Cutting Edge Innovation in Clinical & Experimental PH' session. Features:

  • Sotatercept – eligibility, dosing, results -  Luke Howard, Imperial College London
  • Pulmonary vascular and right heart remodeling: what cardiac imaging and exercise tell us about Sotatercept - Franz Rischard, University of Arizona
  • Genetic background: differential response to Sotatercept? - David Montani, Universite Paris-Saclay
  • Complications of Sotatercept - Rahul Argula, Medical University of South Carolina
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8 January 2025

Webinar presentations: Cardiopulmonary networks: bridging infection and microbiome in pulmonary vascular disease; Inflammasome activation in pulmonary arterial hypertension; Role of oxidative signals in endothelial phenotypes in PH; Spironolactone: an old drug with new tricks; HIPPO/MST signaling via BUB3 and FOXO drives pulmonary vascular cell growth and survival
 

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11 December 2024

Webinar presentations: Hispanic ethnicity and social determinants of health in pulmonary arterial hypertension; Sirtuin 3 and uncoupling protein2, the missing link between genetics, metabolism, and pulmonary arterial hypertension; Estrogen and portopulmonary hypertension: the Pulmonary Vascular Complications of Liver Disease Study; The right heart network and risk stratification in pulmonary arterial hypertension; Pulmonary hypertension caused by autocrine endothelial signaling
 

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13 November 2024

Webinar presentations: The PAH microenvironment: lessons learned from tumor microenvironment mechano-induced cell metabolism changes; Identification of arterial and venous morphologic markers in pulmonary arterial hypertension using CT imaging; The keto diet as treatment for pulmonary hypertension associated with obesity; Endothelial transdifferential from exacerbated inflammatory signaling in BMP9 in lung endothelium; The role of pericytes in the pathophysiology of pulmonary arterial hypertension

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9 October 2024

Webinar presentations: Cellular mechosignaling in pulmonary arterial hypertension; Sex differences in pulmonary arterial hypertension randomized clinical trials; Precapillary pulmonary hypertension and death from COVID-19; Estradiol and estrogen receptor protection of right ventricular function – role of apelin; Prostacyclin reverses right ventricular hypertrophy and dysfunction in severe PAH; Pulmonary vascular complications of heart failure with preserved ejection fraction

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3 September 2024

Webinar presentations: Autophagy and BMPR2 receptor degradation as the cause of PAH; BMPR1A promotes ID2-ZEB1 interaction to suppress endothelial to mesenchymal transition in PAH; Cardiovascular and pulmonary phenotypes for single and double knockout mice deficient in BMP9 and BMP10; BMPR2 – When and where the animal models match patient disease

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10 July 2024

Webinar presentations: Autoantibodies as the cause of PAH; Prevalence and effect of myelofibrosis on PAH; Mast cells as the cause of pulmonary vascular remodelling in PAH; B-cell depletion with rituximab for the treatment of systemic sclerosis-associated PH; Emergency myelopoiesis contributes to immune cell exhaustion in pulmonary vascular remodelling

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14 June 2024

Webinar presentations: Therapeutic efficacy and mechanisms of Drpitor1a in PAH; SNPs for sirtuin3 and uncoupling protein2 are causal of PAH and diabetes disease severity; Mitochondrial control of metabolic, angiogenic, and hematopoietic function in PH onset and progression; Heteroplasmy of wild-type mitochondrial DNA variants causes metabolic heart disease with PH.

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