A001 Targeting ZIP12 to Modulate Intracellular Zinc and Vascular Dysfunction in Pulmonary Arterial Hypertension, A002 Role of The Protein Ttk in the Vascular Remodeling Processes in Pulmonary Artery Hyerpenstion and more.
Placental Abnormalities of Malperfusion, Inflammation, and Meconium are Associated With Persistent Pulmonary Hypertension of the Newborn, Pulmonary Hypertension-Targeted Therapies in Adult and Pediatric Patients Supported With Ventricular Assist Devices: A Systematic Review and more.
Ventilatory inefficiency, assessed by the VE/VCO2 slope during cardiopulmonary exercise testing (CPET), is a key physiological marker. However, differences in ventilatory efficiency between chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary arterial hypertension (PAH), as well as their response to treatment, remain incompletely characterized.
Pulmonary hypertension (PH) is frequently accompanied by a decline in kidney function. In this retrospective cohort, worsening PH was associated with long-term eGFR decline only when accompanied by transition from acute kidney injury (AKI) to acute kidney disease (AKD), defined as persistent kidney dysfunction beyond 7 days after AKI onset, whereas early AKI reversal was not.
Chronic thromboembolic pulmonary hypertension (CTEPH) is rare in adolescents, and evidence regarding balloon pulmonary angioplasty (BPA) in young patients with hereditary thrombophilia remains limited.
Pulmonary hypertension associated with chronic lung disease (PH-CLD) meets precapillary PH criteria. Less is known CLD patients with “early vasculopathy,” a phenotype characterized by elevated pulmonary vascular resistance (PVR) and normal mean pulmonary artery pressure (mPAP).
Sotatercept in Pulmonary Arterial Hypertension: Central, Hematologic, and Peripheral Mechanisms of Benefit Sotatercept improves small airway disease and hyperinflation in patients with pulmonary hypertension
Catheter-directed thrombolysis (CDL) and mechanical thrombectomy (MT) are increasingly used for intermediate–high–risk pulmonary embolism (PE), yet comparative long-term outcomes remain uncertain. We aimed to compare the effectiveness and safety of CDL versus MT in real-world clinical practice.
Pregnancy poses substantial risks for women with Pulmonary Arterial Hypertension (PAH). This study aimed to evaluate maternal and neonatal outcomes in a contemporary PAH cohort under modern management, specifically investigating whether vasoreactive status warrants distinct clinical recommendations.
Sotatercept has recently expanded treatment options for pulmonary arterial hypertension (PAH), but its mental health and quality-of-life impact is not well characterized. We assessed psychiatric diagnoses and patient-reported outcomes in PAH patients treated with sotatercept within the clinical trial program.