Learning and research

Pulmonary arterial hypertension (PAH) is characterized by pulmonary vasoconstriction and vascular remodeling, leading to increased pulmonary vascular resistance, pathological right ventricular (RV) remodeling, and ultimately right heart failure and death. 

In patients with mitral regurgitation (MR), the role of invasive hemodynamics is not well defined. We evaluated the value of right heart catheterization (RHC) and the 2022 ESC/ERS pulmonary hypertension (PH) definition prior to a mitral valve procedure for the prediction of PH several months thereafter. 

Sepsis affects more than 19 million people globally each year, and approximately 50% of sepsis patients develop lung injury. Sepsis-triggered lung injury is characterized by over-activation of inflammatory response and the production of large amounts of inflammatory cytokines.

Traditional echocardiographic measures of right ventricular (RV) function, such as tricuspid annular plane systolic excursion (TAPSE) and peak systolic velocity at the tricuspid annulus (S’), may be unreliable after cardiac surgery due to changes in loading conditions and myocardial mechanics. 

Presented at PVRI 2026 Congress by Paul Hassoun, Johns Hopkins University

Presented at PVRI 2026 Congress by Kurt Prins, Medical University of South Carolina

Presented at PVRI 2026 Congress by Raymond Benza, Sentara Health East Virginia Medical School at Old Dominion University