Bone marrow modulation of pulmonary vascular disease

24 February 2022

A PVRI 2022 Digital webinar

Presentations

  • Reversal of PH by whole bone marrow transplantation in BMPR2 deficient mice, James West 
  • Bone marrow dependency of cigarette smoke-induced PH versus emphysema, Norbert Weissmann
  • Homologous bone marrow transplantation prevents the development of PAH in patients with severe scleroderma, Jason Weatherald
  • Role of bone marrow in the right ventricle remodelling, Gaurav Choudhary

Polls

1.Talk 1: Inflammation and bone marrow-derived cells play an important role in pulmonary vascular remodelling

Agree - 100%

Disagree - 0%

 

2. Talk 2: The inducible nitric oxide synthase in bone marrow-derived cells is a major driver of cigarette smoke-induced pulmonary hypertension in mice

Agree - 82%

Disagree - 18%

 

3. Talk 3: Autologous stem cell transplantation warrants further research as a therapeutic or preventative option for at-risk systemic sclerosis-associated PAH

Agree - 100%

Disagree - 0%

 

4. Talk 4: Bone Marrow derived cells play an important role in RV remodelling in pulmonary hypertension

Agree - 82%

Disagree - 18%

Speakers and moderators

James West, Vanderbilt University Medical Center
Norbert Weissmann, Justus Liebig University Giessen
Jason Weatherald, University of Alberta
Gaurav Choudhary, Brown University
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Other materials on this topic

28 February 2023

February 2023 PVRI Community Call with Jason Zelt

In this Community Call, we discussed: 

  • G9a/GLP Targeting Ameliorates Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension
  • Right Ventricular Maladaptation to Pressure Overload in Fischer Rats is Associated with Profound Deficiency in Adenylate Kinase 1 and Impaired Ventricular Energetics
  • Eliminating Senescent Cells Can Promote Pulmonary Hypertension Development and Progression
PVRI Community Calls
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