Pro-Con debate session 2: Medical vs. surgical or interventional therapy for CTEPH

16 December 2021

A PVRI 2024 Digital webinar

Presentations

  • Riociguat should be given to all CTEPH patients, regardless of timing of PEA/BPA, Ardeschir Ghofrani (PRO) vs Hiromi Matsubara (CON)
  • Systematic follow-up of patients following acute pulmonary embolism is associated with an increased incidence of CTEPH and less severe disease, Charlotte Durrington 
  • Women and chronic thromboembolic pulmonary hypertension. The special meaning of balloon pulmonary angioplasty, Alejandro Cruz-Utrilla
  • G protein-coupled receptor expression from single cell RNA sequencing in chronic thromboembolic pulmonary hypertension, Gayathri Viswanathan
  •  Study of the antifibrotic action of JAK inhibitors for the prevention and treatment of chronic thromboembolic pulmonary hypertension, Andrei Karpov
  • Unilateral CTED: Do they benefit from surgery? Farid Rashidi

Polls

Start of webinar poll

1. Talk 1 & 2: Which statement do you agree with

PRO: Riociguat should be given to all CTEPH patients, regardless of timing of PEA/BPA - 82%

CON: Riociguat should be given only to patients with inoperable or residual CTEPH after PEA/BPA - 18%

 

2. Talk 3: A dedicated PE follow-up clinic can improve diagnostic rates for CTEPH and identify patients with less severe disease

Agree - 91%

Disagree - 9%

 

3. Talk 4: Balloon pulmonary angioplasty will be a more important treatment option for women in comparison with men

Agree - 36%

Disagree - 64%

 

4. Talk 5: Identifying and studying various GPCRs as drug targets for CTEPH would open more therapeutic options for CTEPH patients.

Agree - 91%

Disagree - 9%

 

5. Talk 6: Targeted pharmacological suppression of fibrous vascular wall remodeling may improve prognosis in patients with chronic thromboembolic pulmonary hypertension

Agree - 91%

Disagree - 9%

 

6. Talk 7: Performing Pulmonary Thromboendarterectomy for unilateral CTEPH

Agree - 82%

Disagree - 18%

 

End of webinar poll

1. Talk 1 & 2: Which statement do you agree with

PRO: Riociguat should be given to all CTEPH patients, regardless of timing of PEA/BPA - 76%

CON: Riociguat should be given only to patients with inoperable or residual CTEPH after PEA/BPA - 24%

 

2. Talk 3: A dedicated PE follow-up clinic can improve diagnostic rates for CTEPH and identify patients with less severe disease

Agree - 100%

Disagree - 0%

 

3. Talk 4: Balloon pulmonary angioplasty will be a more important treatment option for women in comparison with men

Agree - 41%

Disagree - 59%

 

4. Talk 5: Identifying and studying various GPCRs as drug targets for CTEPH would open more therapeutic options for CTEPH patients.

Agree - 88%

Disagree - 12%

 

5. Talk 6: Targeted pharmacological suppression of fibrous vascular wall remodeling may improve prognosis in patients with chronic thromboembolic pulmonary hypertension

Agree - 94%

Disagree - 6%

 

6. Talk 7: Performing Pulmonary Thromboendarterectomy for unilateral CTEPH

Agree - 82%

Disagree - 18%

Speakers and moderators

Ardeschir Ghofrani, Justus Liebig University Giessen, Germany
Hiromi Matsubara, Okayama Medical Center
Charlotte Durrington, The University of Sheffield, UK
Alejandro Cruz-Utrilla, The Hospital Universitario 12 de Octubre, Spain
Gayathri Viswanathan, Duke University, USA
Andrei Karpov, Almazov National Medical Research Centre, Russia
Farid Rashidi, University of Saskatchewan
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