Overview of TGFb-BMP pathway

Presented at Genetics-inspired Therapeutics for PH by Marie-Jose Goumans, Leiden University

Summary

Explore the intricate TGF-beta-BMP signaling pathway, a complex cellular conversation crucial for development and disease. This presentation delves into how cells interpret diverse signals through receptor combinations and co-receptors like endoglin, influencing outcomes from quiescence to fibrosis. Understanding these dynamics is key to developing targeted therapies for conditions like pulmonary hypertension.

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