Sotatercept - overview of clinical experience

Presented at Genetics-inspired Therapeutics for PH by Ardeschir Ghofrani, Justus-Liebig-Universität Gießen

Summary

This presentation details clinical experiences with sotatercept, a groundbreaking treatment for Pulmonary Arterial Hypertension (PAH).  It explores its mechanism of action, balancing signaling pathways, and its efficacy demonstrated in multiple clinical trials like Zenith and Hyperion.  The discussion also addresses potential adverse events and the evolving role of BNP as a disease marker in PAH patients treated with sotatercept.

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