Gut-lung crosstalk in Sch-PH

Presented at PVRI 2026 Congress by Suellen D’arc Oliveira, University of Illinois Chicago

Summary

Chronic cystic disease is linked to pulmonary arterial hypertension (PAH), with the gut-lung microbiome, apoptosis, and the P2X7 receptor playing key roles. Research indicates that extracellular ATP and proteins like CRP2 are significant in PAH pathology. Gender differences in disease response are noted, emphasizing the need for more studies in human samples. An upcoming symposium will further explore infection and pulmonary vascular diseases.

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