Transcriptomic signatures of pulmonary vascular remodeling in COPDGene

Presented at PVRI 2026 Congress by Vasile Foris, Medical University of Graz

Summary

The presentation explores the identification of transcriptomic and multi-signatures related to pulmonary vascular disease in patients with a smoking history and COPD. It highlights the role of multidisciplinary collaboration and various cohorts, such as the COPD gene and Framingham heart study. The research focuses on characterising imaging traits, developing biomarkers, and analysing proteomic and transcriptomic data to suggest potential drug targets for further validation.

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