SOX17 enhancer variant reduces endothelial progenitor cells in patients with PAH

Presented at PVRI 2026 Congress by James Klinger, Alpert Medical School of Brown University

Summary

The SOC 17 gene plays a crucial role in pulmonary hypertension, with mutations affecting endothelial cells and influencing treatment options. Understanding genetic variants is vital for grasping disease progression. The discussion also highlights the differentiation of progenitor cells and their therapeutic potential. Various studies underscore the complexity of gene interactions, emphasizing the necessity for ongoing research in this field.

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