Distinct RV vs. LV Macrophage Stress Responses Under Uniform Hypoxia

Presented at PVRI 2026 Congress by Sue Gu, University of Colorado Anschutz 

Summary

The study explores how regional cardiac macrophages respond to hypoxia in PH. It reveals that right ventricular macrophages have a unique early immune response, while septal and left ventricular macrophages respond later. The research highlights the need to examine all cardiac regions to fully understand cardiac adaptation and identify potential therapeutic targets for PH.

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