Fine Particulate Exposure During Pregnancy Impacts on Perinatal Complications in Deeply Phenotyped Preterm Infants With Significant Immaturity

13 May 2026

Caroline Johansson, Yvonne Kraus, Juan David Henao Sanchez, Benjamin Schubert, Kathrin Wolf, Carola Voss, Tobias Stoeger, Tanja Seegmüller, Andreas W. Flemmer, Kai Förster, Marie Standl, Anne Hilgendorff

https://doi.org/10.1002/pul2.70320 

 

Abstract

The identification of ubiquitous risk factors determining long-term morbidity is crucial in infants born prematurely when aiming to develop prevention strategies. In a cohort of deeply phenotyped infants born before 32 weeks gestational age, we successfully demonstrate that exposure to fine particulate matter during pregnancy is associated with increased odds of preeclampsia and altered birth weight percentiles, highlighting potential underlying effects on vascular and metabolic pathology in relation to the degree of immaturity.

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