In this Community Call, we discussed: 

• Elevated Pulmonary Arterial Compliance Is Associated with Survival in Pulmonary Hypertension: Results from a Novel Network Medicine Analysis
• SOX17 Enhancer Variants Disrupt Transcription Factor Binding And Enhancer Inactivity Drives Pulmonary Hypertension
• The UPHILL study: A nutrition and lifestyle intervention to improve quality of life for patients with pulmonary arterial hypertension

In this Community Call, we discussed: 

• Maternal outcomes among pregnant women with congenital heart disease–associated pulmonary hypertension
• Proline and glucose metabolic reprogramming supports vascular endothelial and medial biomass in pulmonary arterial hypertension

In this Community Call, we discussed: 

• Phase 3 Trial of Sotatercept for Treatment of Pulmonary Arterial Hypertension
• Single-Cell Analysis Reveals Distinct Immune and Smooth Muscle Cell Populations that Contribute to Chronic Thromboembolic Pulmonary Hypertension

In this Community Call, we discussed: 

• G9a/GLP Targeting Ameliorates Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension
• Right Ventricular Maladaptation to Pressure Overload in Fischer Rats is Associated with Profound Deficiency in Adenylate Kinase 1 and Impaired Ventricular Energetics
• Eliminating Senescent Cells Can Promote Pulmonary Hypertension Development and Progression

In this Community Call, we discussed: 

• Validity of echocardiographic tricuspid regurgitation gradient to screen for new definition of pulmonary hypertension
• Pulmonary Arterial Hypertension Patients Have a Proinflammatory Gut Microbiome and Altered Circulating Microbial Metabolites