Sotatercept - a case study

8 June 2026

Presented at Genetics-inspired Therapeutics for PH by Luke Howard, Imperial College Healthcare NHS Trust

Summary

This video details the case of Jo, a 33-year-old woman diagnosed with idiopathic pulmonary arterial hypertension (IPAH). It explores her long treatment journey, including responses to sildenafil, ambrisentan, warfarin, iloprost, rituximab, and imatinib. It highlights the striking outcomes seen with sotatercept in the TRoPHY-1 and PULSAR trials, identifying her as an exceptional responder.

 

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Our speaker

Luke Howard, Imperial College Healthcare NHS Trust
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